Behavior reallocations within 24‐h movement profiles and change in cardiometabolic biomarkers during pregnancy
Authors' conclusion
Maintaining or achieving a 24-h movement profile with guideline-recommended amounts of MVPA may be beneficial for reducing pregnancy-induced increases in total and LDL cholesterol.
Study context
- Population
- Pregnant individuals with prepregnancy overweight/obesity; accelerometer-measured waking movement, self-reported sleep, fasting serum biomarkers at 12 and 32 weeks' gestation
- Participants
- 137 individuals
- Exposure
- Reallocations of time within 24-h movement profiles
- Outcome
- Change in cardiometabolic biomarkers from early to late pregnancy
- Follow-up
- 12 to 32 weeks' gestation
Methodological detailscompositional isotemporal substitution models
- Compositional isotemporal substitution models
Main finding
As reported in the abstract
Guideline-recommended MVPA in early pregnancy: reallocating 30 min from MVPA to sleep, sedentary behavior or LPA — greater increase in total cholesterol
0.6 mmol/L
95% CI −0.1 to 1.2
Guideline-recommended MVPA in early pregnancy: reallocating 30 min from MVPA to sleep, sedentary behavior or LPA — greater increase in LDL-C
0.7 mmol/L
95% CI 0.1 to 1.3
Low MVPA in early pregnancy: reallocating 30 min from sleep, sedentary behavior or LPA to MVPA — lower increase in total cholesterol
0.6 mmol/L
95% CI −1.3 to 0.1
Low MVPA in early pregnancy: reallocating 30 min from sleep, sedentary behavior or LPA to MVPA — lower increase in LDL-C
0.8 mmol/L
95% CI −1.4 to −0.1
Observational data: associations, not effects.
Further findings
Biomarker change across pregnancy · early to late pregnancy
- Average increase in biomarkers
- 21%-83%
Other biomarkers
- No associations with change in glucose, insulin, HOMA-IR, very low-density lipoprotein or HDL-C, TG, or free fatty acids
Original publication
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