Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active fast study
An erratum to this article was published (Diabetes Res Clin Pract, Nov 2025 ↗)
Authors' conclusion
Adults with T1DM can safely fast during Ramadan and exercise using the MiniMed™ 780G to manage diabetes. Findings from this study build on the real-world evidence to enhance clinical guidelines for optimal T1DM care using advanced technology.
Study context
- Population
- Adults with T1D using the MiniMed™ 780G
- Participants
- 34 adults
- Exposure
- Ramadan fasting with Moderate-Intensity Exercise (MIE) vs Shawwal with MIE, on MiniMed™ 780G Advanced Hybrid Closed-Loop system (AHCLS)
- Outcome
- Glycemic control (CGM metrics)
Main finding
As reported in the abstract
Median TBR (<70 mg/dL) remained stable across Ramadan and Shawwal (p = 0.39)
1.0 %
TIR (70-180 mg/dL) significantly higher during Ramadan than Shawwal (p = 0.0134)
70.5 % vs 68.5 %
Median TAR (>180 mg/dL) less in Ramadan than Shawwal (p = 0.0088)
29 % vs 30 %
Observational data: associations, not effects.
Further findings
Treatment satisfaction, SmartGuard use and adherence
- High treatment satisfaction and SmartGuard mode usage, with good adherence to fasting and exercise
Safety
Severe hypoglycemia and DKA · Ramadan and Shawwal
- No severe hypoglycemia or DKA occurred
Original publication
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