Associations of updated cardiovascular health metrics, including sleep health, with incident diabetes and cardiovascular events in older adults with prediabetes: A nationwide population-based cohort study
Authors' conclusion
Ideal composite CVH metrics in older adults with prediabetes were associated with a lower risk of diabetes and MACE.
Study context
- Population
- Older adults aged ≥ 65 years with prediabetes; Cardiovascular health (CVH) assessed by seven baseline metrics (modified American Heart Association recommendations, including sleep health)
- Participants
- 7,948 adults
- Exposure
- Intermediate and ideal vs poor composite CVH metrics
- Outcome
- Incident diabetes and MACE
- Follow-up
- Median 11.9 years
Methodological detailsnationwide
- Nationwide
Main finding
As reported in the abstract
Diabetes
Each group vs poorMultivariable-adjusted HR (95% CI)
Intermediate
0.87(0.78–0.96)
Ideal
0.72(0.65–0.79)
- Diabetes cases (overall)
- 2,405 (30.3%)
Observational data: associations, not effects.
Further findings
| Outcome | Multivariable-adjusted HR (95% CI) | |
|---|---|---|
| MACE · median follow-up 11.9 yearsIntermediatevs Poor | 0.99 (0.88–1.11) | |
| MACE · median follow-up 11.9 yearsIdealvs Poor | 0.88 (0.79–0.97) | |
| 0.512Multivariable-adjusted HR (log scale) |
- Major adverse cardiovascular events (MACE) — MACE (overall)
- 2,039 (25.6%)
Diabetes and MACE by age subgroup
- Ideal composite CVH: lower risk of diabetes and MACE in those aged 65-74 years, but not in those aged ≥ 75 years
Original publication
Associations of updated cardiovascular health metrics, including sleep health, with incident diabetes and cardiovascular events in older adults with prediabetes: A nationwide population-based cohort study. Diabetes Res Clin Pract. Published 7 July 2023. doi:10.
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