Association of Spousal Diabetes Status and Ideal Cardiovascular Health Metrics With Risk of Incident Diabetes Among Chinese Adults
Main finding · Incident diabetesResult — go to the resultHazard ratio 1.15 95% CI 1.03–1.30Authors' conclusion
In this study, spousal diabetes diagnosis with uncontrolled HbA1c level was associated with increased risk of incident diabetes, but strict management of spousal HbA1c level and improving ICVHM profiles may attenuate the association of spousal diabetes status with diabetes risk. These findings suggest the potential benefit of couple-based lifestyle or pharmaceutical interventions for diabetes.
Study context
- Population
- Chinese adults without diabetes in the China Cardiovascular Disease and Cancer Cohort, with baseline and follow-up glucose measurements and spouses with baseline glucose measurements; mean (SD) age 56.4 (8.3) years, 48.0% male
- Participants
- 34,821 adults
- Exposure
- Spousal diabetes vs no spousal diabetes
- Outcome
- Incident diabetes (2010 ADA criteria)
- Follow-up
- Mean (SD) 3.6 (0.9) years
Methodological detailsData collected January 2011 to December 2012 and March 2014 to December 2016
- Data collected January 2011 to December 2012 and March 2014 to December 2016
Main finding
Incident diabetes
Hazard ratio
1.15
95% CI 1.03–1.30
As reported in the abstract
Observational data: associations, not effects.
Further findings
Incident diabetes by spousal HbA1c control
- Participants whose spouses had uncontrolled HbA1c: higher risk of diabetes, HR
- 1.20 (1.04-1.39) (95% CI)
- Participants whose spouses had controlled HbA1c: risk did not increase significantly, HR
- 1.10 (0.92-1.30) (95% CI)
Incident diabetes with spousal diabetes, by composite cardiovascular health status (ideal cardiovascular health metrics (ICVHMs))
- Poor cardiovascular health (<4 ICVHMs): associated with spousal diabetes status; 3 ICVHMs, HR
- 1.50 (1.15-1.97) (95% CI)
- Intermediate to ideal cardiovascular health (≥4 ICVHMs): not associated; 4 ICVHMs, HR
- 1.01 (0.69-1.50) (95% CI)
Original publication
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