Associations and predictive performance of 11 anthropometric measures with incident type 2 diabetes: A prospective cohort study from the UK Biobank
Authors' conclusion
Although most adiposity markers were associated with type 2 diabetes, the magnitude of the associations differed. WHtR had the strongest associations and predictive ability for type 2 diabetes and thus could be a more suitable marker for clinical use.
Study context
- Population
- White European UK Biobank participants free of diabetes at baseline
- Participants
- 161,127 participants
- Exposure
- 11 anthropometric measures and incident T2D; predictive performance vs BMI
- Outcome
- Incident T2D
- Follow-up
- Median 10.0 (IQR 9.3-10.8) years
Methodological detailsUK Biobank
- UK Biobank
Main finding
As reported in the abstract
Associations of anthropometric measures with incident T2D
Developed T2D
6315 participants
Waist to height ratio (WHtR), HR per 1-SD increment, women (strongest association)
2.27
95% CI 2.19–2.35
WHtR, HR per 1-SD increment, men (strongest association)
1.96
95% CI 1.90–2.01
Observational data: associations, not effects.
Further findings
Predictive performance (C-index) vs BMI
- WHtR and anthropometric risk index had significantly better T2D risk discrimination than BMI
Original publication
Associations and predictive performance of 11 anthropometric measures with incident type 2 diabetes: A prospective cohort study from the UK Biobank. Obesity (Silver Spring). Published 19 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →