Associations of smoking status and leisure-time physical activity with waist circumference change—10-year follow-up among twin adults
Main finding · WC change (cm)Result — go to the resultAdjusted β 2.04 cm 95% CI 0.94–3.14Authors' conclusion
Smoking cessation seems to be associated with WC increase, but familial confounding may be involved in this process. LTPA appears to mitigate increase in WC independently of smoking status and familial influences.
Study context
- Population
- Twin adults in the FinnTwin16 cohort (46% men) reporting smoking status, leisure-time physical activity (LTPA) and weight circumference (WC) in early adulthood and 10 years later
- Participants
- 3,322 twins
- Exposure
- Smoking status and LTPA with WC change
- Quittersn = 273
- Outcome
- WC change (cm)
- Follow-up
- 10 years
Methodological details10-year follow-up, within-pair fixed-effect analyses, Within-pair analyses among 660 dizygotic and 390 monozygotic twin pairs
- 10-year follow-up
- Within-pair fixed-effect analyses
- Within-pair analyses among 660 dizygotic and 390 monozygotic twin pairs
Main finding
As reported in the abstract
10-year follow-up
Adjusted β
2.04 cm
95% CI 0.94–3.14
Change by group
Quitters
8.4
mean · SD 8.1 · cm
- Each additional MET-h/week of LTPA associated with less WC increase, independently of smoking status (adjusted β; 95% CI −0.07, −0.05); replicated in within-pair analyses
- −0.06
Observational data: associations, not effects.
Further findings
- Smoking cessation among baseline daily smokers · 10-year follow-up — Quitters
- 36.4%
- LTPA change · 10-year follow-up — Quitters
- mean 5.0 (SD 35.0) MET-h/week
LTPA change · 10-year follow-up
- Participants in general decreased LTPA during follow-up, except quitters
Original publication
Associations of smoking status and leisure-time physical activity with waist circumference change—10-year follow-up among twin adults. Int J Obes (Lond). Published 29 June 2025. doi:10.
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