Associations of cord blood leukocyte telomere length with adiposity growth from infancy to adolescence
Main finding · Age of BMI peak (females)Result — go to the resultβ 0.99 95% CI 0.16–1.82Authors' conclusion
LTL at birth may be an early biomarker of altered adiposity growth. Newborn telomere biology may shed new insight into the developmental origins of health and disease.
Study context
- Population
- Children in Project Viva (48% female, 71% White); Body mass index (BMI) trajectories from birth to 18 years
- Participants
- 375 children
- Exposure
- Short vs not short cord blood leukocyte telomere length (LTL)
- Outcome
- Age of BMI peak (females)
Methodological detailsLTL measured from cord blood via duplex quantitative PCR
- LTL measured from cord blood via duplex quantitative PCR
Main finding
As reported in the abstract
β
0.99
95% CI 0.16–1.82
psex interaction = 0.015
Observational data: associations, not effects.
Further findings
| Outcome | βcombined (95% CI) |
|---|---|
| Age of BMI rebound (males and females)Earlier age of rebound | −5.26 (−9.44 to −1.08) |
Original publication
Associations of cord blood leukocyte telomere length with adiposity growth from infancy to adolescence. Pediatr Obes. Published 9 September 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →