Associations of age at first birth and lifetime parity with weight and adiposity across midlife in women from Project Viva
Authors' conclusion
Women who have a first birth before age 23 years or after age 40 years and those with multiple births may benefit from more intensive monitoring for excess adiposity gain.
Study context
- Population
- Women from Project Viva reporting age at first birth and lifetime parity at a midlife visit; mean (SD) age 32.6 (4.9) years at enrollment, 30.4 (5.5) years at first birth, 2.4 (0.9) lifetime births
- Participants
- 735 women
- Comparison
- Age at first birth and lifetime parity categories
- Primary endpoint
- Trajectory of weight, WC and body fat across midlife, measured up to four times after final birth
- Follow-up
- After final birth
Methodological detailslinear mixed-effects regression models, adjusted models
- Linear mixed-effects regression models
- Adjusted models
Primary result
As reported in the abstract
Weight trajectory after final birth
Each group vs age 30 to 34 yearsMean difference, kg (95% CI)
Age <23 years
8.38(4.13–12.63)
Age ≥40 years
6.54(0.64–12.45)
Further findings
Adiposity trajectory by lifetime parity
- Four or more births vs two: higher trajectory of adiposity after accounting for covariates
Original publication
Associations of age at first birth and lifetime parity with weight and adiposity across midlife in women from Project Viva. Obesity (Silver Spring). Published 24 July 2023. doi:10. 1002/ oby. 23831
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