Associations of age at first birth and lifetime parity with weight and adiposity across midlife in women from Project Viva

Obesity (Silver Spring)Published Secondary analysis of the Project Viva cohort

Authors' conclusion

Women who have a first birth before age 23 years or after age 40 years and those with multiple births may benefit from more intensive monitoring for excess adiposity gain.

Study context

Population
Women from Project Viva reporting age at first birth and lifetime parity at a midlife visit; mean (SD) age 32.6 (4.9) years at enrollment, 30.4 (5.5) years at first birth, 2.4 (0.9) lifetime births
Participants
735 women
Comparison
Age at first birth and lifetime parity categories
Primary endpoint
Trajectory of weight, WC and body fat across midlife, measured up to four times after final birth
Follow-up
After final birth
Methodological detailslinear mixed-effects regression models, adjusted models
  • Linear mixed-effects regression models
  • Adjusted models

Primary result

As reported in the abstract

Weight trajectory after final birth
Each group vs age 30 to 34 yearsMean difference, kg (95% CI)
Age <23 years
8.38(4.13–12.63)
Age ≥40 years
6.54(0.64–12.45)

Further findings

Adiposity trajectory by lifetime parity

Four or more births vs two: higher trajectory of adiposity after accounting for covariates

Original publication

Associations of age at first birth and lifetime parity with weight and adiposity across midlife in women from Project Viva. Obesity (Silver Spring). Published 24 July 2023. doi:10.1002/oby.23831

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