Associations Between Gestational Weight Gain and Children's Neurodevelopment at 3 Years of Age

Obesity (Silver Spring)Published Prospective cohort study

Authors' conclusion

Excessive GWG, insufficient GWG, and the Slow-Rapid GWG trajectory showed associations with children's noncompetent neurodevelopment. As GWG is a modifiable factor, these findings could inform early intervention for high-risk mother-child dyads.

Study context

Population
Mother-child pairs from the Jiangsu Birth Cohort
Participants
4,177 mother-child pairs
Exposure
Excessive or insufficient gestational weight gain (GWG) and GWG trajectories vs optimal GWG
Outcome
Noncompetent neurodevelopment (Bayley-III Screening Test)
Follow-up
Age 3 years
Methodological detailsbirth cohort
  • Birth cohort

Main finding

As reported in the abstract

Noncompetent neurodevelopment

Relative risk

1.50

Excessive · noncompetent cognitive risk

Relative risk

1.30

Insufficient · noncompetent fine motor risk

Slow-Rapid trajectory: noncompetent cognitive development
RR = 2.51
Slow-Rapid trajectory: noncompetent expressive communication
RR = 1.94

Observational data: associations, not effects.

Further findings

Noncompetent cognitive development, insufficient vs optimal GWG, by breastfeeding duration · age 3 years

Breastfeeding ≤ 12 months
RR = 2.07
Breastfeeding > 12 months
RR = 0.72

Original publication

Associations Between Gestational Weight Gain and Children's Neurodevelopment at 3 Years of Age. Obesity (Silver Spring). Published 6 April 2026. doi:10.1002/oby.70192

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