Associations between BMI in youth and site‐specific cancer in men—A cohort study with register linkage
Authors' conclusion
This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.
Study context
- Population
- Young men with measured height and weight at conscription (age 18)78,217 developed cancer
- Participants
- 1,489,115 men
- Exposure
- BMI at age 18
- Outcome
- Incident site-specific cancer
- Follow-up
- Mean 31 years
Methodological detailsregister linkage, measured height and weight at age 18
- Register linkage
- Measured height and weight at age 18
Main finding
As reported in the abstract
Site-specific cancer by BMI at age 18
- BMI linearly associated with risk of all 18 site-specific cancers assessed (malignant melanoma; leukemia; myeloma; Hodgkin lymphoma; non-Hodgkin lymphoma; lung, head and neck, CNS, thyroid, esophagus, stomach, pancreas, liver and gallbladder, colon, rectum, kidney, bladder cancer), in some instances evident at BMI usually defined as normal (20-25 kg/m²)
- Higher BMI associated with lower risk of prostate cancer
- Highest HRs and population attributable fractions for some gastrointestinal cancers
- Cox regression adjusted for age, year and site of conscription, parental education
Observational data: associations, not effects.
Original publication
Associations between BMI in youth and site‐specific cancer in men—A cohort study with register linkage. Obesity (Silver Spring). Published 6 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →