Obesity

Socio-economic differences in body mass index: the contribution of genetic factors

Int J Obes (Lond)Published Cross-sectional study

Authors' conclusion

Better understanding of the interplay between genes and environment provides insight into the mechanisms explaining SEP differences in BMI.

Study context

Population
Participants of Finnish health surveys 1992–2017 with measured weight and height, PGS-BMI and register-linked educational attainment, occupation-based social class and personal income; 53% women53% women
Participants
33,523 participants
Exposure
Lower vs higher socioeconomic position
Outcome
BMI differences by socioeconomic position and the contribution of polygenic risk scores of BMI
Methodological detailspooled Finnish health surveys 1992–2017, linked administrative register data, polygenic risk scores
  • Pooled Finnish health surveys 1992–2017
  • Linked administrative register data
  • Polygenic risk scores

Main finding

As reported in the abstract

Adjusted BMI difference, basic vs tertiary education

Men: basic vs tertiary educated, adjusted body mass index (BMI) difference

1.4 kg/m²

95% CI 1.2; 1.6

Women: basic vs tertiary educated, adjusted BMI difference

2.5 kg/m²

95% CI 2.3; 2.8

Observational data: associations, not effects.

Original publication

Socio-economic differences in body mass index: the contribution of genetic factors. Int J Obes (Lond). Published 10 January 2024. doi:10.1038/s41366-024-01459-w

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