Type 2 & other diabetes

The association of weight status with glycemic control, diabetes related complications and anti-hyperglycemic medication use in patients with type 2 diabetes mellitus: The results of the Australian National Diabetes Audit (Australian National Diabetes Audits (ANDA)) 2015–2022

Diabetes Res Clin PractPublished Cross-sectional study

Authors' conclusion

Patients with T2DM and obesity have poorer glycemic control, higher utilisation of anti-glycemic medications and greater odds of diabetes related complications. Approaches to optimise glycemic control that also deliver weight reduction should be an integral component of diabetes management to help improve health outcomes for people with T2DM.

Study context

Population
Adults with T2DM in the Australian National Diabetes Audits (ANDA) 2015–2022; 55.7 % male, mean BMI 33.4 kg/m²
Participants
13,589 adults
Exposure
Obesity vs non-obesity weight status
Outcome
Association of weight status with glycemic control (HbA1c categories)
Methodological detailsnational audit data 2015–2022
  • National audit data 2015–2022

Main finding

As reported in the abstract

Above-target glycemia by weight status
ObesityOdds ratio (95 % CI)
Moderately above target (HbA1c 7.1-9 %)
1.20(1.05–1.37)
Greatly above target (HbA1c > 9 %)
1.43(1.22–1.68)
Above-target glycemia (HbA1c > 7 %), all patients
71 %

Observational data: associations, not effects.

Further findings

Diabetes complications and anti-hyperglycemic drug use

Patients with obesity more likely to have CVD, DFU and peripheral vascular disease, despite use of a greater number of anti-hyperglycemic drugs

Original publication

The association of weight status with glycemic control, diabetes related complications and anti-hyperglycemic medication use in patients with type 2 diabetes mellitus: The results of the Australian National Diabetes Audit (ANDA) 2015–2022. Diabetes Res Clin Pract. Published 20 June 2025. doi:10.1016/j.diabres.2025.112333

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