Association of the triglyceride glucose-body mass index with the extent of coronary artery disease in patients with acute coronary syndromes
Authors' conclusion
TyG-BMI index is linearly associated with the degree of complex coronary artery disease in female ACS patients. However, the inclusion of the TyG-BMI index did not improve the predictive power of the underlying risk model for female ACS patients.
Study context
- Population
- Patients with Acute Coronary Syndrome (ACS) who underwent PCI at the Affiliated Hospital of Zunyi Medical University
- Participants
- 2,317 patients
- Exposure
- TyG-BMI index tertiles
- Outcome
- Mid/high SYNTAX score (>22; intermediate 23-32, high ≥33)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Mid/high SYNTAX score, per TyG-BMI index (overall)
- TyG-BMI index associated with mid/high SYNTAX score: OR 1.0041, 95% CI 1.0000-1.0079, p = 0.0310
- Multivariate logistic regression
Observational data: associations, not effects.
Further findings
Mid/high SYNTAX score in women, per TyG-BMI index
- Independent risk factor after adjusting for confounders: OR 1.0100, 95% CI 1.0000-1.0200, p = 0.0050
- T3 group: OR 2.4900, 95% CI 1.2200-5.0600, p = 0.0120 (2.49 times higher risk)
- Linear correlation with SYNTAX score >22 (restricted cubic spline)
- Subgroup analysis
Added predictive value of TyG-BMI in women
- Net reclassification improvement 0.0867 [−0.0256-0.1989], p = 0.1301
- Integrated discrimination improvement 0.0183 [0.0038-0.0329], p = 0.0135
- Did not improve predictive power of the underlying risk model
Original publication
Association of the triglyceride glucose-body mass index with the extent of coronary artery disease in patients with acute coronary syndromes. Cardiovasc Diabetol. Published 13 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →