Association of multiple sclerosis with incident diabetes: A nationwide cohort study
Main finding · Cumulative incidence of DMResult — go to the resultAdjusted hazard ratio 0.98 95% CI 0.89–1.09Authors' conclusion
This study demonstrated that patients with MS had a similar risk of incident DM as compared to age- and sex matched controls from the background population.
Study context
- Population
- Patients aged 18–99 with multiple sclerosis (MS) and no known diabetes mellitus (DM), Danish nationwide registries; 33 % men; median age 42 years (25th-75th percentile 33–51)matched 1:5
- Participants
- 13,376 vs 66,880
- Exposure
- MS vs matched controls from the background population
- MSn = 13,376
- Controln = 66,880reference
- Outcome
- Incident DM
- Follow-up
- Median 8.3 years (25th-75th percentile, 4.0-13.3)
Methodological detailsregistry-based, matched 1:5 on age and sex
- Registry-based
- Matched 1:5 on age and sex
Main finding
Cumulative incidence of DM
Adjusted hazard ratio
0.98
95% CI 0.89–1.09
By group
MSvs Control
adjusted HR 0.98 (95% CI 0.89–1.09)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Diagnosed with DM during follow-up · median follow-up 8.3 years
| Outcome | HR (95% CI) | P value |
|---|---|---|
| Incident T1DEstimate outside its printed interval | 1.60 (0.98–1.40) | P = 0.07 |
Incident T1D
- Overall risk of incident T1D was low
Original publication
Association of multiple sclerosis with incident diabetes: A nationwide cohort study. Diabetes Metab. Published 22 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →