Association of epicardial adipose tissue on magnetic resonance imaging with cardiovascular outcomes: Quality over quantity?
Authors' conclusion
EAT quality (as assessed via CMR T1 times), but not EAT quantity, is independently associated with a composite endpoint of nonfatal myocardial infarction, heart failure hospitalization, and all-cause death.
Study context
- Population
- All-comer cohort undergoing cardiac magnetic resonance (CMR); 47.2% female, mean age 58.4 years
- Participants
- 966 participants
- Outcome
- Composite of:
- Nonfatal MI
- HF hospitalization
- All-cause death
- Follow-up
- 57.7 months
Methodological detailsprospective observational CMR registry, all-comer cohort
- Prospective observational CMR registry
- All-comer cohort
Main finding
As reported in the abstract
Composite of:
- Nonfatal MI
- HF hospitalization
- All-cause death
Events
280
29.0%
EAT T1 times (EAT-T1), aHR per SD (adjusted for established clinical risk); 95% CI 1.022-1.413; p = 0.026
1.202
Observational data: associations, not effects.
Further findings
Epicardial adipose tissue (EAT) area and EAT-T1
- Mean EAT area
- 7.3 cm²
- Mean EAT-T1
- 268 ms
EAT-T1 vs markers of obesity, dyslipidemia, comorbidities (linear regression)
- EAT-T1 not associated with markers of obesity, dyslipidemia, or comorbidities such as diabetes (p > 0.05 for all)
Original publication
Association of epicardial adipose tissue on magnetic resonance imaging with cardiovascular outcomes: Quality over quantity? Obesity (Silver Spring). Published 28 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →