Association of concurrent diabetes and poor sleep with cognitive decline: a 4-year community-based cohort study
Main finding · Cognitive declineResult — go to the resultAdjusted odds ratio 5.74 95% CI 1.58–18.81Authors' conclusion
The co-occurrence of diabetes and poor sleep was associated with higher odds of cognitive decline
Study context
- Population
- Cognitively normal adults aged ≥40 years in a community-based population
- Participants
- 1,218 adults
- Exposure
- Concurrent DM and poor sleep vs other diabetes/sleep status
- Outcome
- Cognitive decline: decrease of ≥4 points on the Chinese Mini-Mental Status from baseline
- Follow-up
- 4 years
Methodological details4-year follow-up
- 4-year follow-up
Main finding
Cognitive decline
Adjusted odds ratio
5.74
95% CI 1.58–18.81
Concurrent DM and poor sleepvs other diabetes/sleep status
adjusted OR 5.74 (95% CI 1.58–18.81)
As reported in the abstract
- Developed cognitive decline during follow-up (all participants)
- 30 (2.46%)
Observational data: associations, not effects.
Further findings
Cognitive decline by poor sleep component (concurrent with diabetes): poor subjective sleep quality, short sleep duration, low sleep efficiency, frequent sleep disturbances or severe daytime dysfunction · 4 years
- Association evident mainly for these sleep components, rather than prolonged sleep latency (adjusted ORs; all P < 0.05)
- 4.17-10.23
Cognitive decline, sensitivity analysis applying broader criteria for dysglycemia · 4 years
- Adjusted OR with broader criteria for dysglycemia (95% CI: 1.23 - 12.82); corroborated robustness of findings
- 4.10
Original publication
Association of concurrent diabetes and poor sleep with cognitive decline: a 4-year community-based cohort study. Diabetes Res Clin Pract. Published 31 August 2026. doi:10.
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