Association of body mass index and weight change with pneumonia mortality in a Japanese population: Japan Public Health Center-based Prospective Study
Authors' conclusion
Underweight and greater weight change was associated with an increase in the risk of pneumonia mortality in Japanese adults.
Study context
- Population
- Japan Public Health Center (JPHC) Study participants in Japan who completed a questionnaire 1995–1998, followed for death through 2016994 pneumonia deaths
- Participants
- 79,564 participants
- Exposure
- Body mass index (BMI) categories and 5-year weight change vs normal weight / weight change <2.5 kg
- Outcome
- Pneumonia mortality
- Follow-up
- Median 18.9 y
Methodological detailspopulation-based, Cox proportional hazards regression
- Population-based
- Cox proportional hazards regression
Main finding
As reported in the abstract
Pneumonia mortality by baseline BMI
Each group vs normal weightHazard ratio (95% CI)
Underweight
2.29(1.83–2.87)
Overweight
0.63(0.53–0.75)
Observational data: associations, not effects.
Further findings
| Outcome | Multivariable-adjusted HR (95% CI) | |
|---|---|---|
| Pneumonia mortality by 5-year weight changeWeight loss ≥5 kgvs Weight change <2.5 kg | 1.75 (1.46–2.10) | |
| Pneumonia mortality by 5-year weight changeWeight gain ≥5 kgvs Weight change <2.5 kg | 1.59 (1.27–2.00) | |
| 0.512Multivariable-adjusted HR (log scale) |
Original publication
Association of body mass index and weight change with pneumonia mortality in a Japanese population: Japan Public Health Center-based Prospective Study. Int J Obes (Lond). Published 3 March 2023. doi:10.
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