Lipids & metabolic liver disease

Association between the triglyceride glucose-body mass index and future cardiovascular disease risk in a population with Cardiovascular-Kidney-Metabolic syndrome stage 0–3: a nationwide prospective cohort study

Cardiovasc DiabetolPublished Prospective cohort study

Authors' conclusion

This cohort study demonstrated a positive linear association between TyG-BMI index and increased CVD incidence in a population with CKM syndrome stage 0-3. This finding suggests that enhanced assessment of TyG-BMI index may provide a more convenient and effective tool for individuals at risk for CVD in CKM syndrome stage 0-3.

Study context

Population
Population with CKM syndrome stage 0–3, China Health and Retirement Longitudinal Study (CHARLS); 52.62% female, mean age 59.17 ± 9.28 years
Participants
7,376 participants
Exposure
TyG-BMI per 10-unit increase
Outcome
CVD, determined by standardised questionnaire during follow-up
Methodological detailsnationwide
  • Nationwide

Main finding

As reported in the abstract

CVD incidence

Increase in risk of cardiovascular diseases (CVD) per 10-unit increase in TyG-BMI (fully adjusted Cox regression), 95% CI 1.041-1.090

6.5%

Observational data: associations, not effects.

Original publication

Association between the triglyceride glucose-body mass index and future cardiovascular disease risk in a population with Cardiovascular-Kidney-Metabolic syndrome stage 0–3: a nationwide prospective cohort study. Cardiovasc Diabetol. Published 7 August 2024. doi:10.1186/s12933-024-02352-6

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