Lipids & metabolic liver disease
Association between the triglyceride glucose-body mass index and future cardiovascular disease risk in a population with Cardiovascular-Kidney-Metabolic syndrome stage 0–3: a nationwide prospective cohort study
Authors' conclusion
This cohort study demonstrated a positive linear association between TyG-BMI index and increased CVD incidence in a population with CKM syndrome stage 0-3. This finding suggests that enhanced assessment of TyG-BMI index may provide a more convenient and effective tool for individuals at risk for CVD in CKM syndrome stage 0-3.
Study context
- Population
- Population with CKM syndrome stage 0–3, China Health and Retirement Longitudinal Study (CHARLS); 52.62% female, mean age 59.17 ± 9.28 years
- Participants
- 7,376 participants
- Exposure
- TyG-BMI per 10-unit increase
- Outcome
- CVD, determined by standardised questionnaire during follow-up
Methodological detailsnationwide
- Nationwide
Main finding
As reported in the abstract
CVD incidence
Increase in risk of cardiovascular diseases (CVD) per 10-unit increase in TyG-BMI (fully adjusted Cox regression), 95% CI 1.041-1.090
6.5%
Observational data: associations, not effects.
Original publication
Association between the triglyceride glucose-body mass index and future cardiovascular disease risk in a population with Cardiovascular-Kidney-Metabolic syndrome stage 0–3: a nationwide prospective cohort study. Cardiovasc Diabetol. Published 7 August 2024. doi:10. 1186/ s12933-024-02352-6
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