Association between triglyceride glucose-body mass index and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study
Authors' conclusion
A higher TyG-BMI index was proportionally related to an increased incidence of MACCEs in the elderly or female patients. However, the inclusion of the TyG-BMI index did not provide better predictive performance for MACCEs in the elderly, specifically in female patients.
Study context
- Population
- Patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation1,438 analysed
- Participants
- 2,533 patients
- Exposure
- TyG-BMI index tertiles
- Outcome
- MACCEs: composite of acute MI, repeat revascularization, stroke and all-cause mortality
- Follow-up
- 34-month follow-up
Methodological detailsconsecutive participants
- Consecutive participants
Main finding
As reported in the abstract
MACCEs
Incident MACCEs among 1438 participants
195
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| MACCEs in elderly patients (exploratory subgroup, multivariable logistic regression) · 34-month follow-upElderly patients · exploratory subgroup analysis | 1.22 (1.011–1.467) | P = 0.038 | |
| MACCEs in female patients (exploratory subgroup, multivariable logistic regression) · 34-month follow-upFemale patients · exploratory subgroup analysis | 1.33 (1.004–1.764) | P = 0.047 | |
| 0.512Odds ratio (log scale) |
MACCEs in elderly patients (exploratory subgroup, multivariable logistic regression) · 34-month follow-up
- Adding TyG-BMI index to traditional risk factor models did not improve risk prediction for MACCEs in elderly patients
MACCEs in female patients (exploratory subgroup, multivariable logistic regression) · 34-month follow-up
- Adding TyG-BMI index to traditional risk factor models did not improve risk prediction for MACCEs in female patients
Original publication
Association between triglyceride glucose-body mass index and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study. Cardiovasc Diabetol. Published 30 March 2023. doi:10.
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