Association between triglyceride glucose-body mass index and long-term adverse outcomes of heart failure patients with coronary heart disease
Authors' conclusion
This study reveals a nonlinear association between the TyG-BMI index and both all-cause mortality and HF rehospitalization in HF patients with CHD, positioning the TyG-BMI index as a significant prognostic marker in this population.
Study context
- Population
- Heart failure (HF) patients with coronary heart disease (CHD)
- Participants
- 823 patients
- Exposure
- Triglyceride glucose-body mass index (TyG-BMI) index and long-term outcomes
- Outcome
- All-cause mortality and HF rehospitalization
- Follow-up
- 9.4 years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
9.4 years
- Deaths
- 425
- Rehospitalized due to HF
- 484
- Reverse J-shaped relationship with all-cause mortality: decreased risk with higher TyG-BMI below 240.0, adjusted HR
- 0.90 (95% CI 0.86-0.93; Log-likelihood ratio p = 0.003)
- U-shaped relationship with HF rehospitalization, inflection point 228.56: below, adjusted HR
- 0.95 (95% CI 0.91-0.98)
- HF rehospitalization above inflection point 228.56, adjusted HR
- 1.08 (95% CI 1.03-1.13; Log-likelihood ratio p < 0.001)
Observational data: associations, not effects.
Original publication
Association between triglyceride glucose-body mass index and long-term adverse outcomes of heart failure patients with coronary heart disease. Cardiovasc Diabetol. Published 9 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →