Association between the triglyceride-glucose index and subclinical left ventricular systolic dysfunction in obese patients
Authors' conclusion
We concluded that an increase in the TyG index is independently associated with subclinical LV systolic dysfunction in obese patients.
Study context
- Population
- Obese patients, January 2019 to January 2024
- Participants
- 1,028 patients
- Exposure
- High vs low triglyceride-glucose (TyG) index
- Outcome
- LV GLS (subclinical LV systolic function)
Main finding
As reported in the abstract
LV GLS
- Left ventricular (LV) global longitudinal strain (GLS) significantly lower in high vs low TyG index
- High TyG index vs Low TyG index: P = 0.01
Observational data: associations, not effects.
Further findings
LV GLS <20% (multivariable-adjusted)
- TyG index independent risk indicator for LV GLS <20%, OR
- 1.520 (95% CI 1.040 to 2.221; P = 0.031)
- Adjusted for sex, age, BMI, heart rate, hypertension, DM, dyslipidaemia, blood urea nitrogen, serum creatinine, LV mass and LV hypertrophy
Comorbidities
- Greater incidences of hypertension, DM and hyperlipidaemia with high TyG index
Original publication
Association between the triglyceride-glucose index and subclinical left ventricular systolic dysfunction in obese patients. Cardiovasc Diabetol. Published 7 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →