Diabetes complications

Association between mortality and diabetes in patients with acute diseases treated by emergency medical services: A multicenter, prospective cohort study

Diabet MedPublished Prospective cohort study

Authors' conclusion

Diabetes, particularly complications, significantly increases short- and medium-term mortality in patients with acute illnesses treated with emergency services.

Study context

Population
Adults with acute illnesses transported by emergency medical services (EMS) and admitted to emergency departments (EDs), Spain (2019–2022)
Participants
5,963 adults
Exposure
Diabetic patients with complications vs diabetic patients without complications vs nondiabetic patients
Outcome
Mortality
Follow-up
2 years
Methodological detailsmulticenter
  • Multicenter

Main finding

As reported in the abstract

P < 0.001

Overall 2-year mortality
25.4% (n = 1513)

Observational data: associations, not effects.

Secondary outcomes

Mortality predictors in diabetes mellitus (DM) with complications

Main risk factors: advanced age and elevated lactate, leukocyte and bilirubin levels
Protective factors: higher Glasgow Coma Scale scores and hemoglobin levels

Survival curves · acute phase

Sharp decline in survival in DM with complications during the acute phase

Original publication

Association between mortality and diabetes in patients with acute diseases treated by emergency medical services: A multicenter, prospective cohort study. Diabet Med. Published 15 July 2026. doi:10.1111/dme.70427

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