Association between different triglyceride glucose index-related indicators and overactive bladder

Diabetes Res Clin PractPublished Cross-sectional study

Authors' conclusion

Positive associations of TyG-related indicators with OAB were observed. TyG-WHtR has the strongest predictive performance for OAB in the total population.

Study context

Population
Participants aged ≥ 20 years from NHANES 2005–2018
Participants
9,024 participants
Exposure
TyG-related indicators and overactive bladder (OAB)
Outcome
Association between three TyG-related indicators and OAB
Methodological detailsNHANES 2005-2018, weighted multivariate logistic regression, subgroup and interaction analyses
  • NHANES 2005-2018
  • Weighted multivariate logistic regression
  • Subgroup and interaction analyses

Main finding

As reported in the abstract

Association of TyG-related indicators with OAB
Associations statistically different in age and physical activity subgroups
all p for interaction < 0.1

Observational data: associations, not effects.

Further findings

Predictive ability for OAB, whole population

TyG-WHtR highest predictive ability, largest AUC
0.625 (95 %CI: 0.609, 0.641)
TyG-WHtR relatively more predictive in the < 60 years and moderate-to-vigorous physical activity subgroups

Original publication

Association between different triglyceride glucose index-related indicators and overactive bladder. Diabetes Res Clin Pract. Published 22 March 2025. doi:10.1016/j.diabres.2025.112128

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