Association between the cumulative average triglyceride glucose-body mass index and cardiovascular disease incidence among the middle-aged and older population: a prospective nationwide cohort study in China
Authors' conclusion
Our study revealed a noteworthy correlation between the cumulative average TyG-BMI and incident CVD among the middle-aged and older population. The cumulative average TyG-BMI emerges as a valuable tool that may enhance the primary prevention and treatment of CVD.
Study context
- Population
- Middle-aged and older adults in China (China Health and Retirement Longitudinal Study (CHARLS)); 53.6% female, mean age 59.6 (SD 8.8) years
- Participants
- 5,418 participants
- Exposure
- Cumulative average triglyceride glucose-body mass index (TyG-BMI)
- Outcome
- Incident CVD
- Follow-up
- 4-year follow-up
Methodological detailsCHARLS, Exposure: average of TyG-BMI at Wave 1 (2011) and Wave 3 (2015)
- CHARLS
- Exposure: average of TyG-BMI at Wave 1 (2011) and Wave 3 (2015)
Main finding
As reported in the abstract
Participants developing cardiovascular disease (CVD)
543
10.0%
Fully adjusted OR per 1 SD increase in cumulative average TyG-BMI
1.168, 1.040-1.310
95% CI
Restricted cubic spline (RCS): positive, linear association (P for overall; P for nonlinear)
P for overall = 0.038
P for nonlinear = 0.436
Observational data: associations, not effects.
Further findings
- Mean (SD) cumulative average TyG-BMI, all participants
- 204.9 (35.7)
Original publication
Association between the cumulative average triglyceride glucose-body mass index and cardiovascular disease incidence among the middle-aged and older population: a prospective nationwide cohort study in China. Cardiovasc Diabetol. Published 6 January 2024. doi:10.
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