Association between cumulative atherogenic index of plasma exposure and risk of myocardial infarction in the general population
Authors' conclusion
Long-term cumulative exposure to AIP and the time course of AIP accumulation increased the risk of MI. High AIP earlier resulted in a greater risk increase than later in life with the same time-weighted cumulative AIP, emphasizing the importance of controlling atherogenic dyslipidemia early in life.
Study context
- Population
- General population, Kailuan study
- Participants
- 54,440 participants
- Exposure
- Higher vs lower cumulative atherogenic index of plasma (AIP) exposure and AIP accumulation time course
- Outcome
- Incident MI
- Follow-up
- 11.05 years
Main finding
As reported in the abstract
Hazard ratio (95% CI)
Highest time-weighted cumulative AIP quartile
1.89(1.47–2.43)
Longest duration of high AIP
1.52(1.18–1.95)
High cumulative AIP and negative slope
1.42(1.13–1.79)
- Incident myocardial infarction (MI) cases
- 766
Observational data: associations, not effects.
Original publication
Association between cumulative atherogenic index of plasma exposure and risk of myocardial infarction in the general population. Cardiovasc Diabetol. Published 17 August 2023. doi:10.
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