Type 2 & other diabetes

Association between cardiovascular disease risk and incident type 2 diabetes mellitus in individuals with prediabetes: A retrospective cohort study

Diabetes Res Clin PractPublished Retrospective cohort study

Main finding · Incident T2DMResult — go to the resultAdjusted hazard ratio 1.30 95 % CI 1.06–1.60

Authors' conclusion

Among patients with prediabetes, those with high CVD risk were more likely to develop incident T2DM, as determined by the FRS. CVD risk factors should be properly evaluated and managed in individuals with prediabetes to reduce the risk of both incident T2DM and associated cardiovascular complications.

Study context

Population
Individuals with prediabetes who underwent health check-ups at the Asan Medical Center
Participants
5,908 individuals
Exposure
Moderate- to high-CVD risk vs low-CVD risk
  • Moderate- to high-riskn = 3,031
Outcome
Incident T2DM
Follow-up
Median 5.2 years

Main finding

As reported in the abstract

Adjusted hazard ratio

1.30

95 % CI 1.06–1.60

P = 0.011

Events by group

Moderate- to high-riskvs Low-risk
aHR 1.30 (95 % CI 1.06–1.60); P = 0.011

Observational data: associations, not effects.

Original publication

Association between cardiovascular disease risk and incident type 2 diabetes mellitus in individuals with prediabetes: A retrospective cohort study. Diabetes Res Clin Pract. Published 1 February 2024. doi:10.1016/j.diabres.2024.111125

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