Association between cardiovascular disease risk and incident type 2 diabetes mellitus in individuals with prediabetes: A retrospective cohort study
Main finding · Incident T2DMResult — go to the resultAdjusted hazard ratio 1.30 95 % CI 1.06–1.60Authors' conclusion
Among patients with prediabetes, those with high CVD risk were more likely to develop incident T2DM, as determined by the FRS. CVD risk factors should be properly evaluated and managed in individuals with prediabetes to reduce the risk of both incident T2DM and associated cardiovascular complications.
Study context
- Population
- Individuals with prediabetes who underwent health check-ups at the Asan Medical Center
- Participants
- 5,908 individuals
- Exposure
- Moderate- to high-CVD risk vs low-CVD risk
- Moderate- to high-riskn = 3,031
- Outcome
- Incident T2DM
- Follow-up
- Median 5.2 years
Main finding
As reported in the abstract
Adjusted hazard ratio
1.30
95 % CI 1.06–1.60
P = 0.011
Events by group
Moderate- to high-riskvs Low-risk
aHR 1.30 (95 % CI 1.06–1.60); P = 0.011
Observational data: associations, not effects.
Original publication
Association between cardiovascular disease risk and incident type 2 diabetes mellitus in individuals with prediabetes: A retrospective cohort study. Diabetes Res Clin Pract. Published 1 February 2024. doi:10. 1016/ j. diabres. 2024. 111125
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