Gestational diabetes & diabetes in pregnancy
Association between atherogenic index of plasma and gestational diabetes mellitus: a prospective cohort study based on the Korean population
Authors' conclusion
This study revealed that the AIP at 10-14 weeks of gestation was independently and positively correlated with GDM risk. AIP could serve as an early screening and monitoring tool for pregnant women at high risk of GDM, thereby optimizing GDM prevention strategies.
Study context
- Population
- Korean singleton pregnant women; mean age 32.06 ± 3.76 years; Atherogenic index of plasma (AIP) measured at 10–14 weeks of gestation
- Participants
- 585 women
- Comparison
- AIP and gestational diabetes mellitus (GDM) risk
- Primary endpoint
- Association between AIP and GDM, and AIP's predictive capability for GDM
Methodological detailslogistic regression, curve fitting, sensitivity analyses, subgroup analyses, ROC analysis
- Logistic regression
- Curve fitting
- Sensitivity analyses
- Subgroup analyses
- ROC analysis
Primary result
As reported in the abstract
GDM per AIP
- Adjusted OR for GDM with AIP (positive linear relationship)
- OR 1.58, 95% CI 1.27-1.97
- P for non-linearity
- 0.801
- AUC of AIP for GDM
- 0.7879 (95% CI 0.7087-0.8671)
- Optimal AIP cut-off
- 0.3557
- Sensitivity at cut-off
- 72.22%
- Specificity at cut-off
- 75.41%
- GDM incidence
- 6.15%
- Mean AIP
- 0.24 ± 0.20
Further findings
- Association between AIP and GDM robust in sensitivity and subgroup analyses
Original publication
Association between atherogenic index of plasma and gestational diabetes mellitus: a prospective cohort study based on the Korean population. Cardiovasc Diabetol. Published 5 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →