Association Between Antidepressants and Antianxiety Medications and Weight Gain in Korean Adults Aged 19 to 39 Years
Authors' conclusion
Using antidepressants and antianxiety medications may contribute to an increased risk of weight gain among Korean young adults. The potential risk for weight gain should be considered when those medications are used and the prevention of weight gain is needed.
Study context
- Population
- Korean adults aged 19 to 39 years with Korean National Health Insurance Service health examinations more than twice, 2009–2019; mean age 29.4 ± 4.7 years, BMI 23.0 ± 3.6
- Participants
- 792,022 adults
- Exposure
- Antidepressants and/or antianxiety medications vs neither
- Outcome
- Weight gain of 10 kg/year or more
Methodological detailsmultivariable logistic regression, Korean National Health Insurance Service health examinations
- Multivariable logistic regression
- Korean National Health Insurance Service health examinations
Main finding
As reported in the abstract
Weight gain ≥10 kg/year
Rate ratio (95% CI)
Only antianxiety medicationsvs Neither
1.77(1.69–1.85)
Bothvs Neither
3.04(2.91–3.18)
- Between Only antidepressants and Neither
- rate ratio 2.15 (95% CI 2.05–2.0)
Observational data: associations, not effects.
Original publication
Association Between Antidepressants and Antianxiety Medications and Weight Gain in Korean Adults Aged 19 to 39 Years. J Clin Endocrinol Metab. Published 6 August 2024. doi:10.
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