Association between adherence to EAT-Lancet diet and risk of sarcopenia and sarcopenic obesity in adults
Authors' conclusion
Our study indicated that adherence to the EAT-Lancet diet was associated with a lower risk of sarcopenia and sarcopenic obesity, with this association partially mediated by inflammatory biomarkers.
Study context
- Population
- Adults in the National Health and Nutrition Examination Survey; EAT-Lancet score from 24-hour dietary recall
- Participants
- 9,672 adults
- Exposure
- Highest vs lowest quartile of EAT-Lancet diet score
- Outcome
- Prevalence of sarcopenia and sarcopenic obesity
Methodological detailsNHANES, weighted multivariate logistic regression, restricted cubic splines, mediation analysis
- NHANES
- Weighted multivariate logistic regression
- Restricted cubic splines
- Mediation analysis
Main finding
As reported in the abstract
Each group vs lowest quartileEstimate (95% CI)
Highest quartile
OR (sarcopenia) 0.72(0.54–0.95)
Highest quartile
OR (sarcopenic obesity) 0.58(0.42–0.82)
Observational data: associations, not effects.
Further findings
Prevalence of sarcopenia and sarcopenic obesity
- Sarcopenia
- 910 (9.41%)
- Sarcopenic obesity
- 607 (6.28%)
Per 10-point increase in EAT-Lancet score
- OR for sarcopenia
- 0.90 (0.84-0.98) (95% CI)
- OR for sarcopenic obesity
- 0.86 (0.79-0.93) (95% CI)
Mediation by inflammatory biomarkers
- White blood cell count had the strongest mediating effect, followed by C-reactive protein, systemic inflammation response index and systemic inflammatory index
Original publication
Association between adherence to EAT-Lancet diet and risk of sarcopenia and sarcopenic obesity in adults. Int J Obes (Lond). Published 10 November 2025. doi:10.
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