Pituitary & hypothalamus

Assessment of sarcopenic obesity in patients with acromegaly

PituitaryPublished Cross-sectional study

Authors' conclusion

SO is present in patients with acromegaly and is associated with notable functional impairments despite increased muscle mass.

Study context

Population
Patients with acromegaly followed at a tertiary center and age- and sex-matched controls
Participants
48 vs 48
Exposure
Patients with acromegaly vs matched controls
  • AGn = 48
  • CGn = 48reference
Outcome
Prevalence of sarcopenic obesity (ESPEN and EASO Consensus criteria)
Methodological detailsobservational, single tertiary centre, age- and sex-matched controls
  • Observational
  • Single tertiary centre
  • Age- and sex-matched controls

Main finding

As reported in the abstract

Prevalence of sarcopenic obesity

P = 0.006

Observational data: associations, not effects.

Further findings

OutcomeP value
Body composition and physical performanceImpaired strength, gait speed and balance in AGP < 0.05

Body composition and physical performance

AG had greater total and appendicular lean mass
AG showed significant impairments in physical performance, particularly strength, gait speed and balance

Original publication

Assessment of sarcopenic obesity in patients with acromegaly. Pituitary. Published 3 February 2025. doi:10.1007/s11102-024-01494-w

Composed by AI from the published abstract and checked against it. How Briefs are made →

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