Assessment of sarcopenic obesity in patients with acromegaly
Authors' conclusion
SO is present in patients with acromegaly and is associated with notable functional impairments despite increased muscle mass.
Study context
- Population
- Patients with acromegaly followed at a tertiary center and age- and sex-matched controls
- Participants
- 48 vs 48
- Exposure
- Patients with acromegaly vs matched controls
- AGn = 48
- CGn = 48reference
- Outcome
- Prevalence of sarcopenic obesity (ESPEN and EASO Consensus criteria)
Methodological detailsobservational, single tertiary centre, age- and sex-matched controls
- Observational
- Single tertiary centre
- Age- and sex-matched controls
Main finding
As reported in the abstract
Prevalence of sarcopenic obesity
P = 0.006
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Body composition and physical performanceImpaired strength, gait speed and balance in AG | P < 0.05 |
Body composition and physical performance
- AG had greater total and appendicular lean mass
- AG showed significant impairments in physical performance, particularly strength, gait speed and balance
Original publication
Assessment of sarcopenic obesity in patients with acromegaly. Pituitary. Published 3 February 2025. doi:10. 1007/ s11102-024-01494-w
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