Obesity

Assessing the evidence for health benefits of low-level weight loss: a systematic review

Int J Obes (Lond)Published Systematic review

Authors' conclusion

Our findings suggest that low-level weight loss can lead to various health benefits and challenges the conventional threshold for effective weight loss.

Study context

Population
Individuals with excess weight in intervention studies assessing the impact of <5% weight loss on physical or mental health markers or indices70 studies · 68 articles
Comparison
Low-level weight loss
Outcome
Any measured physical or mental health markers or indices
Methodological detailsany language, any country, no time constraints, 7 academic databases, Study participants ranged from 14 to 10,742
  • Any language, any country, no time constraints
  • 7 academic databases
  • Study participants ranged from 14 to 10,742

Pooled result

As reported in the abstract

Health markers or indices with low-level weight loss

Studies reporting improvements

60%

Studies with no change or mixed results

37%

Studies observing worsening of health markers or indices

3%

Participants reporting improvements in health markers or indices (n = 15,839)

87%

Further pooled results

Health markers assessed

Total health markers
137
Metabolic markers
42
Cardiovascular markers
32
Anthropometric measures
19
Quality of life indices
10
Inflammatory biomarkers
10
Renal and hepatic markers
9
Psychosocial and behavioural measures
8
Pulmonary function
3
Total mortality
2
Ovulatory function
1
Muscle strength
1

Original publication

Assessing the evidence for health benefits of low-level weight loss: a systematic review. Int J Obes (Lond). Published 1 November 2024. doi:10.1038/s41366-024-01664-7

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