All-in-one sensor design with overlapping sensor transition reduces automode interruptions and improves patient-reported outcomes in adolescents with type 1 diabetes: real-world evidence from simplera sync integration
Authors' conclusion
Overlapping sensor transition was associated with increased automated delivery, modest glycaemic improvement and reduced device burden.
Study context
- Population
- Adolescents with T1D (median age 12.0 years) established on SmartGuard ≥ 6 months, using the Minimed 780G system; 14 centres
- Participants
- 42 adolescents14 centres
- Exposure
- Simplera Sync vs Guardian 4 sensor
- Outcome
- Time in automated mode
- Follow-up
- Final 2 weeks of each sensor
Methodological detailsmulticentre, before-after, Both observation windows within school term; no pump settings changed
- Multicentre
- Before-after
- Both observation windows within school term; no pump settings changed
Main finding
As reported in the abstract
Time in automated mode increased from 95.3% to 97.1%
+1.8 percentage points, ≈23 min/day
p < 0.02
Observational data: associations, not effects.
Further findings
TIR (70-180 mg/dL) · final 2 weeks of each sensor
- TIR (70-180 mg/dL) increased from 76.7% to 79.3%
- P < 0.05
Mean glucose · final 2 weeks of each sensor
- Mean glucose fell from 146.0 to 141.3 mg/dL
- P < 0.05
Time above 250 mg/dL · final 2 weeks of each sensor
- Time above 250 mg/dL decreased from 3.0% to 2.0%
- P < 0.01
Hypoglycaemia
- No worsening of hypoglycaemia
Patient-reported outcomes (Diabetes Intrusiveness, Difficulty and Self-care Scale)
- Treatment satisfaction increased and perceived burden decreased
- both p < 0.01
Safety
- No worsening of hypoglycaemia
Original publication
All-in-one sensor design with overlapping sensor transition reduces automode interruptions and improves patient-reported outcomes in adolescents with type 1 diabetes: real-world evidence from simplera sync integration. Diabetes Res Clin Pract. Published 17 September 2026. doi:10.
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