Type 1 diabetes

Early and sustained diabetes technology exposure is associated with cognitive outcomes in youth with type 1 diabetes

Diabetes Res Clin PractPublished Prospective observational cohort study

Authors' conclusion

Early and sustained CGM/AID were associated with more favorable verbal cognitive and general ability outcomes in youth with T1D, supporting a potential neuroprotective role of advanced diabetes technologies.

Study context

Population
Children and adolescents (6–17 years) with pediatric-onset T1D
Participants
153 children
Exposure
Continuous glucose monitoring (CGM) and automated insulin delivery (AID) use vs lower or no use
Outcome
Associations of CGM and AID use with WISC-IV scores

Main finding

As reported in the abstract

  • Sustained CGM: P = 0.005
  • Higher AID: P = 0.025
  • Sustained CGM: P = 0.015
  • Higher AID: P = 0.043

Observational data: associations, not effects.

Further findings

Overall cognitive profile

High-average full-scale IQ with relative working-memory weakness

HbA1c ≤ 7 % [53 mmol/mol] during first 2-5 years after diagnosis

Associated with better verbal reasoning, executive-function and behavioral profiles

Socioeconomic status

Lower socioeconomic status associated with higher internalizing symptoms

Original publication

Early and sustained diabetes technology exposure is associated with cognitive outcomes in youth with type 1 diabetes. Diabetes Res Clin Pract. Published 17 September 2026. doi:10.1016/j.diabres.2026.113548

Composed by AI from the published abstract and checked against it. How Briefs are made →

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