Alignment Between 24-h Light-Dark and Activity-Rest Rhythms Is Associated With Diabetes and Glucose Metabolism in a Nationally Representative Sample of American Adults
Authors' conclusion
The alignment pattern between 24-h activity-rest and light-dark cycles may be a critical factor in metabolic health.
Study context
- Population
- Adults aged 20–80 years, National Health and Nutrition Examination Survey (NHANES) 2011–2014, with actigraphy-measured multiday 24-h activity and light data
- Participants
- ∼7,000 adults
- Exposure
- Quintiles of light-activity alignment (phasor magnitude and phasor angle): most impaired vs most proper alignment
- Outcome
- Diabetes
Methodological detailsnationally representative, actigraphy-measured, phasor analysis, multinomial logistic regression
- Nationally representative
- Actigraphy-measured
- Phasor analysis
- Multinomial logistic regression
Main finding
As reported in the abstract
Odds ratio (95% CI)
Phasor magnitude: most impaired quintilevs Phasor magnitude Q5
1.76(1.39–2.24)
Phasor angle: most impaired quintilevs Phasor angle Q1
1.73(1.34–2.25)
Observational data: associations, not effects.
Further findings
Biomarkers of glucose metabolism
- Similar associations observed for biomarkers for glucose metabolism
Subgroups
- Results generally consistent across sociodemographic and obesity groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Alignment Between 24-h Light-Dark and Activity-Rest Rhythms Is Associated With Diabetes and Glucose Metabolism in a Nationally Representative Sample of American Adults. Diabetes Care. Published 21 September 2023. doi:10.
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