Albuminuria trajectories following intensive lifestyle intervention with or without bariatric surgery in adolescents with and at risk of type 2 diabetes
Authors' conclusion
Bariatric surgery combined with lifestyle intervention was associated with sustained reductions in albuminuria, suggesting a potential renoprotective effect in high-risk adolescents.
Study context
- Population
- Adolescents aged 15–17 years with BMI ≥ 35 kg/m², with or at risk of T2D (19 Māori or Pacific; 8 prediabetes, 9 T2D), New Zealand11 female
- Participants
- 20 adolescents
- Exposure
- Intensive lifestyle intervention with bariatric surgery vs without surgery
- Outcome
- Trajectory of log-UACR
- Follow-up
- 36 months
Methodological detailslongitudinal mixed-effects models
- Longitudinal mixed-effects models
Main finding
As reported in the abstract
Change in urine albumin-creatinine ratio (UACR)
Surgical
86%
reduction · CI 72–92
Non-surgical
+2
change · CI - 7 to + 12 · %
P < 0.001
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Albuminuria trajectories following intensive lifestyle intervention with or without bariatric surgery in adolescents with and at risk of type 2 diabetes. Diabetes Res Clin Pract. Published 7 May 2026. doi:10.
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