Albuminuria, Disease Duration, and Glycated Hemoglobin Are Related With Bone Mineral Density in Type 1 Diabetes: A Cross-sectional Study
Authors' conclusion
Studied factors specific to T1D, including albuminuria, disease duration, and HbA1c have an association with BMD regardless of BMI, age, and sex.
Study context
- Population
- Adults with T1D, tertiary care center; 59% women, 16% menopause; median age 33 (26–42) years; median disease duration 19.5 (12–27) years
- Participants
- 128 adults
- Outcome
- Association of HbA1c, disease duration, albuminuria and glomerular filtration rate with BMD (DXA)
Methodological detailssingle tertiary care centre
- Single tertiary care centre
Main finding
As reported in the abstract
Factors associated with BMD (adjusted linear models)
- Higher albuminuria associated with lower femoral neck and total hip bone mineral density (BMD)
- P < .01
- Longer disease duration associated with lower femoral neck and total hip BMD
- P < .05
- Higher HbA1c associated with lower spine BMD
- P < .01
Observational data: associations, not effects.
Original publication
Albuminuria, Disease Duration, and Glycated Hemoglobin Are Related With Bone Mineral Density in Type 1 Diabetes: A Cross-sectional Study. Endocr Pract. Published 22 February 2023. doi:10. 1016/ j. eprac. 2023. 02. 005
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