Osteoporosis, bone & mineral

Albuminuria, Disease Duration, and Glycated Hemoglobin Are Related With Bone Mineral Density in Type 1 Diabetes: A Cross-sectional Study

Endocr PractPublished Cross-sectional study

Authors' conclusion

Studied factors specific to T1D, including albuminuria, disease duration, and HbA1c have an association with BMD regardless of BMI, age, and sex.

Study context

Population
Adults with T1D, tertiary care center; 59% women, 16% menopause; median age 33 (26–42) years; median disease duration 19.5 (12–27) years
Participants
128 adults
Outcome
Association of HbA1c, disease duration, albuminuria and glomerular filtration rate with BMD (DXA)
Methodological detailssingle tertiary care centre
  • Single tertiary care centre

Main finding

As reported in the abstract

Factors associated with BMD (adjusted linear models)
Higher albuminuria associated with lower femoral neck and total hip bone mineral density (BMD)
P < .01
Longer disease duration associated with lower femoral neck and total hip BMD
P < .05
Higher HbA1c associated with lower spine BMD
P < .01

Observational data: associations, not effects.

Original publication

Albuminuria, Disease Duration, and Glycated Hemoglobin Are Related With Bone Mineral Density in Type 1 Diabetes: A Cross-sectional Study. Endocr Pract. Published 22 February 2023. doi:10.1016/j.eprac.2023.02.005

Composed by AI from the published abstract and checked against it. How Briefs are made →

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