Age-standardized incidence, mortality rate, and trend changes of thyroid cancer in the Balearic Islands during the 2000–2020 period: a population-based study
Authors' conclusion
The incidence of TC has grown in the 2000-2020 period in the Balearic Islands, but MR has not changed. Beyond other factors, a significant contribution of overdiagnosis to this increased incidence is likely due to changes in the routine management of thyroid nodular disease and increased availability of neck US.
Study context
- Population
- Thyroid cancer (TC) incident cases from 2000 to 2020, Balearic Islands region
- Participants
- 1,387 incident TC cases
- Exposure
- 2010-2020 period vs 2000-2009 period
- Outcome
- Age-standardized incidence rate (ASIR) of TC
- Follow-up
- 2000–2020
Methodological detailsPublic Health System database review, period comparison 2000-2009 vs 2010-2020
- Public Health System database review
- Period comparison 2000-2009 vs 2010-2020
Main finding
As reported in the abstract
ASIR (×105)
P < 0.001
- Overall age-standardized incidence rate (ASIR) (×105)
- 5.01
- Increment in EAPC
- 7.82%
Observational data: associations, not effects.
Further findings
Tumor size · reduction in tumor size
P < 0.001
| Outcome | 2010-2020 | 2000-2009 | Increase | P value |
|---|---|---|---|---|
| Age at diagnosisSignificant increase in 2010-2020 | 52.11 | 47.32 | P < 0.001 | |
| Micropapillary TC | 6.31% | P < 0.05 |
Disease-specific mortality rate
- Disease-specific mortality rate (MR) remained stable (×105)
- 0.21
Age at diagnosis by mortality
- Mean age at diagnosis for all mortality groups older than survivors (P < 0.001)
Original publication
Age-standardized incidence, mortality rate, and trend changes of thyroid cancer in the Balearic Islands during the 2000–2020 period: a population-based study. Eur Thyroid J. Published 21 April 2023. doi:10.
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