Age But Not Menopausal Status Is Linked to Lower Resting Energy Expenditure
Authors' conclusion
We demonstrated that REEadj declines with age in women before late adulthood, also when controlling partially for genetic background, and that menopause may not contribute to this decline.
Study context
- Population
- Women aged 17–58 years, including 16 mother-daughter pairs; group III by menopausal status: pre- or perimenopausal, postmenopausal, postmenopausal MHT userspre- or perimenopausal 19 · postmenopausal 30 · postmenopausal MHT users 10
- Participants
- 120 women16 mother-daughter pairs
- Exposure
- Younger women vs middle-aged women; menopausal statuses within group III
- Group In = 26
- Group IIn = 35
- Group IIIn = 59reference
- Outcome
- Fat-free mass and fat mass-adjusted resting energy expenditure (REEadj), by indirect calorimetry
Methodological detailsmother-daughter pairs
- Mother-daughter pairs
Main finding
As reported in the abstract
REEadj
Each group vs group IIIDifference, kcal/day (95% CI)P value
Group I
126(93–160)
P < 0.001Group II
88(49–127)
P < 0.001Observational data: associations, not effects.
Further findings
| Outcome | Difference (kcal/day) (95% CI) | P value | |
|---|---|---|---|
| REEadj, daughtersvs their middle-aged mothers | 100 (63–138) | P < 0.001 | |
| −1000100200Difference, kcal/day (linear scale) |
REEadj by menopausal status and sex hormones in group III
- REEadj was not lower in postmenopausal women and did not vary by sex hormone concentrations
Original publication
Age But Not Menopausal Status Is Linked to Lower Resting Energy Expenditure. J Clin Endocrinol Metab. Published 2 June 2023. doi:10.
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