Adrenal disease

Adrenal and juxta‐adrenal schwannomas: A single‐centre study

Clin Endocrinol (Oxf)Published Retrospective cohort study

Authors' conclusion

Adrenal and juxta-adrenal schwannomas are nonfunctioning benign tumours that present with indeterminate radiographic features, including large tumour size and increased unenhanced CT attenuation. We did not find an imaging phenotype that was diagnostic of schwannoma. The diagnosis of this rare tumour is based on biopsy or resection.

Study context

Population
Patients with a histopathologic diagnosis of adrenal or juxta-adrenal schwannoma, single centre, 1995–2022
Participants
24 patients
Exposure
Adrenal schwannoma vs juxta-adrenal schwannoma
  • Adrenal schwannoman = 8
  • Juxta-adrenal schwannoman = 16
Outcome
Clinical, biochemical and imaging characteristics
Follow-up
At diagnosis
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Discovered incidentally on imaging
21, 88%
All tumours unilateral; left
15 (62%)
Right
9 (38%)
Median tumour size
4 cm (range, 2-13 cm)
Round or oval
16 (70%)
Lobulated
7 (30%)
Solid
15 (68%)
Solid-cystic
7 (32%)
Heterogeneous
14 (61%)
Homogeneous
9 (39%)
Median unenhanced CT attenuation
30 Hounsfield units (HU) (range, 12-38 HU)

Observational data: associations, not effects.

Further findings

Tumour size by type · at diagnosis · smaller with adrenal schwannoma

P = 0.037

Original publication

Adrenal and juxta‐adrenal schwannomas: A single‐centre study. Clin Endocrinol (Oxf). Published 4 May 2023. doi:10.1111/cen.14927

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