Thyroid disease

Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes

Eur Thyroid JPublished Retrospective cohort study

Authors' conclusion

Overweight and obese patients have a trend for more thyroid nodules and have a higher risk of being diagnosed with thyroid malignancy.

Study context

Population
Patients with thyroid nodules, categorized by body mass index (BMI); grayscale ultrasonographic (US) and fine-needle aspiration cytology evaluated
Participants
310 patients
Exposure
BMI ≥25 kg/m² vs BMI <25 kg/m²
Outcome
Number of thyroid nodules

Main finding

As reported in the abstract

BMI ≥ 25 kg/m²

4.25

± 2.42

BMI < 25 kg/m²

3.66

± 1.93

P = 0.05

Observational data: associations, not effects.

Further findings

OutcomeP value
Suspicious and malignant cytologyMore suspicious and malignant cytology with BMI ≥ 25 kg/m²P = 0.029

Nodules with intermediate and high suspicion sonographic patterns

More with BMI ≥ 25 kg/m²; not statistically significant

Original publication

Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes. Eur Thyroid J. Published 9 December 2024. doi:10.1530/etj-24-0176

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