Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated with lower visceral and hepatic lipid content in recent‐onset type 1 diabetes and type 2 diabetes
Main findingResult — go to the resultDifference in HLC per 5 points −1.5 % CI −2.7% to −0.3%Authors' conclusion
A shift to a DASH-like diet was associated with favourable VAT and HLC changes, which were partly explained by changes in anthropometric measures and Adipo-IR.
Study context
- Population
- People with recent-onset T1D and T2D from the German Diabetes Study111 in 5-year change analysis
- Participants
- 335 people
- Exposure
- Per 5-point higher DASH score
- Outcome
- Associations of DASH score with SAT and VAT volume and hepatic lipid content (HLC)
Methodological detailsGerman Diabetes Study, multivariable linear regression by diabetes type, mediation analysis, 5-year follow-up
- German Diabetes Study
- Multivariable linear regression by diabetes type
- Mediation analysis
- 5-year follow-up
Main finding
As reported in the abstract
baseline
Difference in hepatic lipid content (HLC) per 5 points
−1.5 %
CI −2.7% to −0.3%
T2D
difference in HLC per 5 points −1.5 % (CI −2.7% to −0.3%)
Observational data: associations, not effects.
Further findings
| Outcome | Change in VAT (cm³) (CI) | |
|---|---|---|
| Change in VAT per 5-point increase in DASH score · 5 yearsT2D | −514 (−800 to −228) | |
| Change in VAT per 5-point increase in DASH score · 5 yearsT1D · imprecise | −403 (−861 to 55) | |
| −1000−5000500Difference, cm³ (linear scale) |
| Outcome | Change in HLC (%) (CI) | |
|---|---|---|
| Change in HLC per 5-point increase in DASH score · 5 yearsImprecise | −1.3 (−2.8% to 0.3%) | |
| −4−202Difference, % (linear scale) |
Change in VAT per 5-point increase in DASH score · 5 years
- BMI and waist circumference changes explained 8%-48% of DASH–VAT change associations in both groups
Change in HLC per 5-point increase in DASH score · 5 years
- In T2D, Adipo-IR changes explained 47% of DASH–HLC change association
Original publication
Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated with lower visceral and hepatic lipid content in recent‐onset type 1 diabetes and type 2 diabetes. Diabetes Obes Metab. Published 15 July 2024. doi:10.
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