Adherence and Clinical Effectiveness of a Subcutaneous Insulin Clinical Decision Support Tool in Hospitalized Patients

J Diabetes Sci TechnolPublished Retrospective cohort study

Main finding · Any euglycemia (70-180 mg/dL)Result — go to the resultOdds ratio 1.30 95% CI 1.04–1.63

Authors' conclusion

Use of an EMR-integrated insulin CDS tool was associated with modest glycemic improvements.

Study context

Population
Adult inpatients with diabetes and hyperglycemia admitted to 2 academic medical centers, December 1, 2015 to July 30, 2018
Participants
1,750 matched patients
Exposure
Use of an electronic medical record (EMR)-embedded subcutaneous insulin clinical decision support (CDS) tool within 24 hours of admission vs matched controls
Outcome
Any euglycemia (70-180 mg/dL)
Follow-up
Day 2
Methodological detailspropensity score matching with Crump trimming and 1:3 nearest-neighbor matching, 2 academic medical centers
  • Propensity score matching with Crump trimming and 1:3 nearest-neighbor matching
  • 2 academic medical centers

Main finding

As reported in the abstract

Odds ratio

1.30

95% CI 1.04–1.63

P = 0.02

By group

Tool usevs Matched controls
OR 1.30 (95% CI 1.04–1.63); P = 0.02

Observational data: associations, not effects.

Further findings

Mean glucose, hypoglycemia and hyperglycemia

Mean glucose levels, hypoglycemia, and hyperglycemia did not differ significantly

Tool uptake on day 1

Admissions with tool use on day 1
662 (12.1%)
Tool use more common with T1D, CKD or higher baseline glucose; varied by diagnosis and provider type

Adherence: total daily insulin dose within 20% of user-selected dose, among patients for whom the tool was used

Patients receiving total daily insulin dose within 20% of user-selected dose
43.7%

Original publication

Adherence and Clinical Effectiveness of a Subcutaneous Insulin Clinical Decision Support Tool in Hospitalized Patients. J Diabetes Sci Technol. Published 30 July 2026. doi:10.1177/19322968261468379

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