Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study
An erratum to this article was published (Diabetologia, Mar 2025 ↗)
Authors' conclusion
Individuals with diabetes experience disparities during inpatient care following NSTEMI. They have a higher risk of long-term mortality than those without diabetes, and higher quality inpatient care may lead to better long-term survival.
Study context
- Population
- Adults hospitalised with NSTEMI, January 2005–March 2019, UK Myocardial Ischaemia National Audit Project (MINAP) registry
- Participants
- 456,376 adults
- Exposure
- Diabetes vs no diabetes
- Outcome
- Long-term mortality by diabetes status
Methodological detailsregistry-based, linked with Office for National Statistics death reporting
- Registry-based
- Linked with Office for National Statistics death reporting
Main finding
As reported in the abstract
Mortality, diabetes vs no diabetes · 30 days, 1, 5 and 10 years
Diabetes vs No diabetesHazard ratio (95% CI)
30 days
1.19(1.15–1.23)
1 year
1.28(1.26–1.31)
5 years
1.36(1.34–1.38)
10 years
1.39(1.36–1.42)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Mortality by inpatient care quality (OBQI score category) in diabetes, vs poor careGood carevs Poor careDiabetes group | 0.74 (0.73–0.76) | |
| Mortality by inpatient care quality (OBQI score category) in diabetes, vs poor careExcellent carevs Poor careDiabetes group | 0.69 (0.68–0.71) | |
| Mortality, excellent vs poor care, diet- and insulin-treated diabetes subgroupsExcellent carevs Poor careDiet-treated | 0.64 (0.61–0.68) | |
| Mortality, excellent vs poor care, diet- and insulin-treated diabetes subgroupsExcellent carevs Poor careInsulin-treated | 0.69 (0.66–0.72) | |
| 0.512Hazard ratio (log scale) |
Baseline characteristics and revascularisation (PCI or CABG)
- Median age, diabetes vs no diabetes
- 74 vs 73 years
- Asian ethnicity, diabetes vs no diabetes
- 13% vs 4%
- Revascularisation, diabetes vs no diabetes (less frequent with diabetes)
- 38% vs 40%
Original publication
Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study. Diabetologia. Published 3 October 2024. doi:10. 1007/ s00125-024-06281-7
Composed by AI from the published abstract and checked against it. How Briefs are made →