Cohort profile: The DIabetes and ST-segment Elevation Myocardial Infarction (DISTEMI) Study
Authors' conclusion
The DISTEMI study integrates comprehensive cardiometabolic phenomic with multiomic profiling to identify cardiometabolic STEMI subtypes and predictors of outcomes, and to improve precision risk stratification and targeted prevention.
Study context
- Population
- Humans with different degrees of glucose tolerance after recent STEMIcurrently included
- Participants
- 100 participants
- Outcome
- Changes in glycemia and insulin sensitivity derived from the OGTT and their relationships to cardiac function
- Follow-up
- 2 and 12 months after STEMI
Methodological detailsMultiomics of blood, urine and stool samples, Cardiometabolic phenotyping at 2 and 12 months after STEMI: Oral glucose tolerance test (OGTT), modified Botnia clamp-test, MRI/spectroscopy/elastography, high-resolution respirometry
- Multiomics of blood, urine and stool samples
- Cardiometabolic phenotyping at 2 and 12 months after STEMI: OGTT, modified Botnia clamp-test, MRI/spectroscopy/elastography, high-resolution respirometry
Main finding
As reported in the abstract
Participants with T2D
Proportion of included participants with T2D
29%
Observational data: associations, not effects.
Original publication
Cohort profile: The DIabetes and ST-segment Elevation Myocardial Infarction (DISTEMI) Study. Cardiovasc Diabetol. Published 13 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →