Adaptive vs Monthly Support for Weight-Loss Maintenance: A Randomized Clinical Trial
Authors' conclusion
In this randomized clinical trial, participants in both conditions were successful at maintaining initial weight loss 20 months after the end of a weight-loss program, but providing extended care on an adaptive schedule did not confer additional benefit vs the once-per-month static schedule. Future research should investigate whether more precise algorithms of high-risk periods for weight regain can be developed and whether these models can improve weight maintenance outcomes. Moreover, given success of participants in both conditions at maintaining initial weight loss, future research should also investigate methods of improving the implementation and dissemination potential of telephone-based extended care interventions.
Study context
- Population
- Adults with obesity who lost ≥5% of baseline weight in a 16-week weight-loss program, areas within driving distance of Gainesville, Florida; mean age 50.6 years, 82.0% women
- Participants
- 255 adults
- Comparison
- Telephone-based extended care on an adaptive vs static schedule
- Adaptiven = 128
- Staticn = 127reference
- Primary endpoint
- Weight change from month 4 (end of initial intervention) to month 24
- Follow-up
- Month 4 to month 24
Methodological detailsConducted October 2019 to November 2024, 20 months of telephone-based extended care delivered individually by a trained interventionist
- Conducted October 2019 to November 2024
- 20 months of telephone-based extended care delivered individually by a trained interventionist
Primary result
As reported in the abstract
Further findings
Proportion maintaining weight loss ≥5% · month 24
Mean
| Outcome | Adaptive | Static |
|---|---|---|
| Weight loss maintained from initial intervention baseline · month 24 | 8.1% (SD 7.8%) | 7.9% (SD 8.5%) |
Proportion maintaining weight loss ≥5% · month 24
- Not a significant difference
Original publication
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