Diabetes technology

Accuracy of a Continuous Glucose Monitoring System Under Hyperglycemic Challenge in Chinese Hospitalized Patients With Diabetes

J Diabetes Sci TechnolPublished Diagnostic accuracy study

Authors' conclusion

Continuous glucose monitoring maintained good accuracy during hyperglycemic challenges in hospitalized patients with diabetes. The time lag was influenced by the rate of glucose change, showing prolongation during the rapid glucose rise phase (0-60 minutes).

Study context

Population
Hospitalized adults (≥18 years) with type 1 and 2 DM
Participants
116 adults580 CGM-PG pairs
Comparison
Sibionics continuous glucose monitoring (CGM) vs plasma glucose
Outcome
Accuracy: MARD, %15/15, %20/20, %30/30, %40/40 agreement rates
Methodological detailssteamed bread meal tolerance test (75 g carbohydrates)
  • Steamed bread meal tolerance test (75 g carbohydrates)

Performance

As reported in the abstract

Accuracy of CGM vs PG during steamed bread meal tolerance test (SBMTT)
Overall mean absolute relative difference (MARD)
11.83%
%15/15 agreement rate
69.5%
%20/20 agreement rate
86.2%
%30/30 agreement rate
98.3%
%40/40 agreement rate
99.7%
Diabetes Technology Society (DTS) error grid: CGM points in zones A and B
100%
DTS error grid: zone A
86%
DTS error grid: zone B
14%
Overall CGM lag time (after minimizing MARD)
5 minutes
CGM lag time at 30 minutes (rapid glucose rise)
10 minutes
CGM lag time at 60 minutes (rapid glucose rise)
20 minutes

Further findings

DTS error grid

Zones A and B
100%
Zone A
86%
Zone B
14%

CGM lag time vs plasma glucose (PG)

Minutes

Overall lag time
5
Lag at 30 minutes
10
Lag at 60 minutes
20
  • After minimizing MARD; increased during rapid glucose rise (0-60 minutes)

Original publication

Accuracy of a Continuous Glucose Monitoring System Under Hyperglycemic Challenge in Chinese Hospitalized Patients With Diabetes. J Diabetes Sci Technol. Published 23 May 2026. doi:10.1177/19322968261442573

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