Obesity

A sequential deep learning model for predicting people with obesity in adults aged 18–64 using physical fitness variables

Int J Obes (Lond)Published Prediction model development study

Authors' conclusion

This explainable sequential deep learning model accurately predicts people with obesity using physical fitness variables and highlights the critical role of cardiorespiratory fitness in obesity risk assessment and management.

Study context

Population
Adults with nationally representative physical fitness data, collected between 2010 and 2023
Participants
204,334 adults
Outcome
Prediction of obesity
Methodological detailssequential deep learning model, stratified 5-fold cross-validation, explainable (SHAP and LIME), nationally representative data
  • Sequential deep learning model
  • Stratified 5-fold cross-validation
  • Explainable (SHAP and LIME)
  • Nationally representative data

Performance

As reported in the abstract

Overall accuracy across five stratified folds (p < 0.001 vs. random)
0.87-0.88
Fold 4 accuracy
0.873
Fold 4 precision
0.866
Fold 4 recall
0.855
Fold 4 F1
0.876
Fold 4 ROC-AUC
0.95
Fold 4 TN
1,462
Fold 4 FN
184
Fold 4 FP
249
Fold 4 TP
1,554

Further findings

Error metrics (fold 4 model)

MAE
0.122
MSE
0.041
R²
0.833
Average prediction error, first 50 samples
0.171

SHAP feature importance (top predictors)

20-m shuttle run estimated VO₂max
0.339
Gender
0.2481
Relative grip strength
0.135

LIME interpretation

LIME intercept
0.511
LIME predicted
0.668
LIME R²
0.995
Low estimated VO₂max (< 28.71 ml/kg/min) and low relative grip strength (< 38.17%) substantially increased probability of obesity classification, particularly among females

Original publication

A sequential deep learning model for predicting people with obesity in adults aged 18–64 using physical fitness variables. Int J Obes (Lond). Published 20 March 2026. doi:10.1038/s41366-026-02053-y

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