Obesity

A randomized‐controlled trial to evaluate the app‐based multimodal weight loss program zanadio for patients with obesity

Obesity (Silver Spring)Published Randomised controlled trial

Authors' conclusion

This study showed that adults with obesity who have used zanadio achieved a significant and clinically relevant weight loss within 12 months and improved further obesity-related health variables compared with a control group. Because of its effectiveness and flexible applicability, the app-based multimodal treatment zanadio might alleviate the present care gap for patients with obesity in Germany.

Study context

Population
Adults with obesityrandomized
Participants
150 adults
Comparison
App-based multimodal weight loss program zanadio vs wait list control
Primary endpoint
Weight change (% of initial weight)
Follow-up
12 months
Methodological detailsConducted January 2021 to March 2022; end points assessed every 3 months for up to 1 year via telephone interviews and online questionnaires
  • Conducted January 2021 to March 2022; end points assessed every 3 months for up to 1 year via telephone interviews and online questionnaires

Primary result

As reported in the abstract

Intervention

−7.75

mean · 95% CI −9.66%–-5.84% · %

Wait list control

0.00

mean · 95% CI −1.98%–1.99% · %

Secondary outcomes

Quality of life, well-being, waist to height ratio · 12 months

All secondary end points improved significantly in the intervention group
Significantly greater improvements in well-being and waist to height ratio vs control

Original publication

A randomized‐controlled trial to evaluate the app‐based multimodal weight loss program zanadio for patients with obesity. Obesity (Silver Spring). Published 26 April 2023. doi:10.1002/oby.23744

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