Type 2 & other diabetes

A preliminary randomized trial of a brief dissonance‐based type 2 diabetes prevention programme for adults with pre‐diabetes

Diabetes Obes MetabPublished Randomised controlled trial

Authors' conclusion

Project Health T2D produced encouraging reductions in body fat, weight and T2D incidence, and increases in lean mass, and is less intensive than other lifestyle modification T2D prevention programme, suggesting that it might be useful to evaluate in a fully powered efficacy trial with a longer follow-up.

Study context

Population
Adults with pre-diabetes
Participants
62 adults
Comparison
Project Health T2D vs educational video control
Methodological detailspreliminary
  • Preliminary

Primary result

As reported in the abstract

Body composition (body fat, weight, BMI, lean mass) · post-test and 3-month follow-up
Greater reduction with Project Health T2D
d (body fat reduction, post-test) 0.76; P = 0.002
Greater reduction with Project Health T2D
d (body fat reduction, 3-month follow-up) 1.07; P < 0.001
Greater reduction with Project Health T2D
d (weight reduction, post-test) 0.59; P = 0.030
Greater reduction with Project Health T2D
d (weight reduction, 3-month follow-up) 0.65; P = 0.017
Greater reduction with Project Health T2D
d (BMI reduction, post-test) 0.60; P = 0.030
Greater reduction with Project Health T2D
d (BMI reduction, 3-month follow-up) 0.67; P = 0.014
Greater increase with Project Health T2D
d (lean mass increase, post-test) 0.80; P = 0.003
Greater increase with Project Health T2D
d (lean mass increase, 3-month follow-up) 0.93; P = 0.001

Further findings

T2D incidence · total 5-month observation period

OR 4.52 · P = 0.096

OutcomedP value
HbA1c reduction · 3-month follow-upMarginally greater reduction with Project Health T2D0.54P = 0.056
FPG · 3-month follow-upNot significantly greater reduction0.25P = 0.364
  • T2D incidence: marginally greater 75% reduction in T2D onset with Project Health T2D

Original publication

A preliminary randomized trial of a brief dissonance‐based type 2 diabetes prevention programme for adults with pre‐diabetes. Diabetes Obes Metab. Published 7 January 2025. doi:10.1111/dom.16170

Composed by AI from the published abstract and checked against it. How Briefs are made →

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