A preliminary randomized trial of a brief dissonance‐based type 2 diabetes prevention programme for adults with pre‐diabetes
Authors' conclusion
Project Health T2D produced encouraging reductions in body fat, weight and T2D incidence, and increases in lean mass, and is less intensive than other lifestyle modification T2D prevention programme, suggesting that it might be useful to evaluate in a fully powered efficacy trial with a longer follow-up.
Study context
- Population
- Adults with pre-diabetes
- Participants
- 62 adults
- Comparison
- Project Health T2D vs educational video control
Methodological detailspreliminary
- Preliminary
Primary result
As reported in the abstract
Body composition (body fat, weight, BMI, lean mass) · post-test and 3-month follow-up
- Greater reduction with Project Health T2D
- d (body fat reduction, post-test) 0.76; P = 0.002
- Greater reduction with Project Health T2D
- d (body fat reduction, 3-month follow-up) 1.07; P < 0.001
- Greater reduction with Project Health T2D
- d (weight reduction, post-test) 0.59; P = 0.030
- Greater reduction with Project Health T2D
- d (weight reduction, 3-month follow-up) 0.65; P = 0.017
- Greater reduction with Project Health T2D
- d (BMI reduction, post-test) 0.60; P = 0.030
- Greater reduction with Project Health T2D
- d (BMI reduction, 3-month follow-up) 0.67; P = 0.014
- Greater increase with Project Health T2D
- d (lean mass increase, post-test) 0.80; P = 0.003
- Greater increase with Project Health T2D
- d (lean mass increase, 3-month follow-up) 0.93; P = 0.001
Further findings
T2D incidence · total 5-month observation period
OR 4.52 · P = 0.096
| Outcome | d | P value |
|---|---|---|
| HbA1c reduction · 3-month follow-upMarginally greater reduction with Project Health T2D | 0.54 | P = 0.056 |
| FPG · 3-month follow-upNot significantly greater reduction | 0.25 | P = 0.364 |
- T2D incidence: marginally greater 75% reduction in T2D onset with Project Health T2D
Original publication
A preliminary randomized trial of a brief dissonance‐based type 2 diabetes prevention programme for adults with pre‐diabetes. Diabetes Obes Metab. Published 7 January 2025. doi:10. 1111/ dom. 16170
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