Diabetes technology

A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings

J Diabetes Sci TechnolPublished Model development and validation study

Authors' conclusion

The GRI is a single-number summary of the quality of glycemia. Its hypoglycemia and hyperglycemia components provide actionable scores and a graphical display (the GRI Grid) that can be used by clinicians and researchers to determine the glycemic effects of prescribed and investigational treatments.

Study context

Population
Insulin-treated adults with diabetes with 14-day continuous glucose monitor (CGM) tracings; tracings ranked by 330 clinicians highly experienced with CGM analysis330 clinician raters
Participants
225 adults
Outcome
Correspondence of GRI with clinician rankings of overall quality of glycemia
Methodological detailsbalanced incomplete block design, principal component analysis, multiple regression
  • Balanced incomplete block design
  • Principal component analysis
  • Multiple regression

Performance

As reported in the abstract

Correlation of combined GRI with clinician rankings

r = 0.95

Original publication

A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings. J Diabetes Sci Technol. Published 29 March 2022. doi:10.1177/19322968221085273

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